2019 UCSD Head & Neck Cancer Center Directors’ Retreat

UCSD Head & Neck Cancer Center 2019 Symposium:
Bioinformatics & Radiomics in Head and Neck Cancer
November 15, 2019- Altman CTRI Auditorium -8:30 AM – 3:45 PM

All are welcome! Precision medicine invokes the use of biomarkers and targeted therapies to deliver personalized treatment approaches. Often this involves leveraging large amounts of biological and clinical data for prognostication and informing treatment decisions. This year, the 2019 UCSD Head & Neck Cancer Center Directors’ Retreat Symposium draws special attention to developments in bioinformatics and radiomics, and how these approaches can help predict treatment responses, optimize treatment delivery, and improve the therapeutic ratio of head and neck cancer treatment.

AGENDA

8:30 AM – 9:15 AM 

Breakfast begins at 8:30 AM @ ACTRI – West Terrace

9:15 AM – 9:30 AM
Introduction to Radiomics in Head and Neck Cancer

Loren Mell, MD
Professor & Vice Chair, Clinical & Translational Research
Director, Center for Precision Radiation Medicine
Department of Radiation Medicine
University of California San Diego

9:30 AM – 9:45 AM
Introduction to Computational Analysis in Head and Neck Cancer

Joe Califano, MD
Professor and Physician-In-Chief
Director, UCSD Center for Head and Neck Cancer
Department of Otolaryngology
University of California San Diego

9:45 AM – 10:55 AM
Early Morning Session

9:45 – 10:05 AM
Microscopic foundation of multimodal human imaging

Anders Dale, PhD
Professor & Vice Chair for Research
Director, Center for Translational Imaging and Precision Medicine
Department of Radiology
University of California San Diego

10:05 – 10:15 AM
Discussion

10:15 – 10:45 AM
INVITED KEYNOTE SEMINAR 1
Deep Learning to Derive Imaging Based
Biomarkers of Cancer Outcomes

Sanjay Aneja, MD
Assistant Professor
Department of Therapeutic Radiology
Yale University

10:45 – 10:55 AM
Discussion

10:55 AM – 11:10 AM
Morning Break

11:10 AM– 12:20 PM
Late Morning Session
ACTRI – Auditorium
11:10 – 11:30 AM
Developing Computational Models of Biological Systems Based on Boolean Implication Network

Debashis Sahoo, PhD
Assistant Professor
Department of Pediatrics
Department of Computer Science and Engineering
University of California San Diego

11:30 – 11:40 AM
Discussion

11:40 – 12:10 AM
INVITED KEYNOTE SEMINAR 2

Computational Analysis to Improve Image
Guided HN Treatment and Toxicity
Assessment

Kristy Brock, PhD
Professor
Dept. of Imaging Physics
Dept. of Radiation Physics
MD Anderson Cancer Center Houston, TX

12:10 – 12:20 PM
Discussion

12:20 PM – 1:05 PM
Lunch, Discussion and External -ACTRI – West

Leadership Feedback -Terrace

1:05 PM – 2:15 PM Early Afternoon Session ACTRI – Auditorium

1:05 – 1:25 PM
Systematic identification of cancer dependencies using combinatorial CRISPR-Cas9 screening and visible machine learning

Brent Kuenzi, PhD
Post-Doctoral Scholar
University of California San Diego

1:25 – 1:35 PM Discussion

1:35 – 2:05 PM
The Repertoire of Mutational Signatures in Human Cancer

Ludmil Alexandrov, PhD
Assistant Professor
Department of Cellular and Molecular Medicine
Assistant Professor of Bioengineering

2:05 – 2:15 PM Discussion

2:15 PM – 2:30 PM Break

2:30 PM – 3:40 PM Final Session

2:30 – 2:50 PM Delineating Cellular and Immune Tumor States and Archetypes

Pablo Tamayo, PhD
Professor of Medical Genetics
Director, Center for Cancer Target Discovery and Development
University of California San Diego

2:50 – 3:00 PM Discussion

3:00 – 3:30 PM
INVITED KEYNOTE SEMINAR 3

RNA you ready for this? Scissor: Shape changes in selecting sample outliers in RNA-seq

Neil Hayes, MD, MS, MPH
Assistant Dean for Cancer Research
Scientific Director, UT-West Institute for Cancer Research
Department of Medicine, Division of Hematology & Oncology
University of Tennessee Health Science Center

3:30 – 3:40 PM Discussion

3:40 – 3:45 PM Closing Remarks

Loren K. Mell, MD
Professor & Vice Chair, Clinical & Translational Research
Director, Center for Precision Radiation Medicine
Department of Radiation Medicine
University of California San Diego

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